Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi-lineage commitment

How the epigenetic landscape is established in development is still being elucidated. Here, we uncover Developmental Pluripotency Associated 2 and 4 (Dppa2/4) as epigenetic priming factors that establish a permissive epigenetic landscape at a subset of developmentally important bivalent promoters ch...

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Detaylı Bibliyografya
Yayımlandı:Nat Struct Mol Biol
Asıl Yazarlar: Eckersley-Maslin, Mélanie A., Parry, Aled, Blotenburg, Marloes, Krueger, Christel, Ito, Yoko, Franklin, Valar Nila Roamio, Narita, Masashi, D’Santos, Clive S., Reik, Wolf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614975/
https://ncbi.nlm.nih.gov/pubmed/32572255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0443-3
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