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Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi-lineage commitment
How the epigenetic landscape is established in development is still being elucidated. Here, we uncover Developmental Pluripotency Associated 2 and 4 (Dppa2/4) as epigenetic priming factors that establish a permissive epigenetic landscape at a subset of developmentally important bivalent promoters ch...
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| Izdano u: | Nat Struct Mol Biol |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614975/ https://ncbi.nlm.nih.gov/pubmed/32572255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0443-3 |
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