Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

Large-scale brain bulk-RNAseq studies identified molecular pathways implicated in Alzheimer’s disease (AD), however these findings can be confounded by cellular composition changes in bulk-tissue. To identify cell intrinsic gene expression alterations of individual cell types, we designed a bioinfor...

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Bibliographic Details
Published in:Mol Neurodegener
Main Authors: Wang, Xue, Allen, Mariet, Li, Shaoyu, Quicksall, Zachary S., Patel, Tulsi A., Carnwath, Troy P., Reddy, Joseph S., Carrasquillo, Minerva M., Lincoln, Sarah J., Nguyen, Thuy T., Malphrus, Kimberly G., Dickson, Dennis W., Crook, Julia E., Asmann, Yan W., Ertekin-Taner, Nilüfer
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359236/
https://ncbi.nlm.nih.gov/pubmed/32660529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00392-6
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