Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

Large-scale brain bulk-RNAseq studies identified molecular pathways implicated in Alzheimer’s disease (AD), however these findings can be confounded by cellular composition changes in bulk-tissue. To identify cell intrinsic gene expression alterations of individual cell types, we designed a bioinfor...

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Publié dans:Mol Neurodegener
Auteurs principaux: Wang, Xue, Allen, Mariet, Li, Shaoyu, Quicksall, Zachary S., Patel, Tulsi A., Carnwath, Troy P., Reddy, Joseph S., Carrasquillo, Minerva M., Lincoln, Sarah J., Nguyen, Thuy T., Malphrus, Kimberly G., Dickson, Dennis W., Crook, Julia E., Asmann, Yan W., Ertekin-Taner, Nilüfer
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359236/
https://ncbi.nlm.nih.gov/pubmed/32660529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00392-6
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