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Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

Cerebral amyloid angiopathy (CAA) contributes to accelerated cognitive decline in Alzheimer’s disease (AD) dementia and is a common finding at autopsy. The APOEε4 allele and male sex have previously been reported to associate with increased CAA in AD. To inform biomarker and therapeutic target disco...

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書誌詳細
出版年:Acta Neuropathol Commun
主要な著者: Reddy, Joseph S., Allen, Mariet, Ho, Charlotte C. G., Oatman, Stephanie R., İş, Özkan, Quicksall, Zachary S., Wang, Xue, Jin, Jiangli, Patel, Tulsi A., Carnwath, Troy P., Nguyen, Thuy T., Malphrus, Kimberly G., Lincoln, Sarah J., Carrasquillo, Minerva M., Crook, Julia E., Kanekiyo, Takahisa, Murray, Melissa E., Bu, Guojun, Dickson, Dennis W., Ertekin-Taner, Nilüfer
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147512/
https://ncbi.nlm.nih.gov/pubmed/34020725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01199-2
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