Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

Cerebral amyloid angiopathy (CAA) contributes to accelerated cognitive decline in Alzheimer’s disease (AD) dementia and is a common finding at autopsy. The APOEε4 allele and male sex have previously been reported to associate with increased CAA in AD. To inform biomarker and therapeutic target disco...

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Gepubliceerd in:Acta Neuropathol Commun
Hoofdauteurs: Reddy, Joseph S., Allen, Mariet, Ho, Charlotte C. G., Oatman, Stephanie R., İş, Özkan, Quicksall, Zachary S., Wang, Xue, Jin, Jiangli, Patel, Tulsi A., Carnwath, Troy P., Nguyen, Thuy T., Malphrus, Kimberly G., Lincoln, Sarah J., Carrasquillo, Minerva M., Crook, Julia E., Kanekiyo, Takahisa, Murray, Melissa E., Bu, Guojun, Dickson, Dennis W., Ertekin-Taner, Nilüfer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147512/
https://ncbi.nlm.nih.gov/pubmed/34020725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01199-2
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