Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

Large-scale brain bulk-RNAseq studies identified molecular pathways implicated in Alzheimer’s disease (AD), however these findings can be confounded by cellular composition changes in bulk-tissue. To identify cell intrinsic gene expression alterations of individual cell types, we designed a bioinfor...

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Bibliografski detalji
Izdano u:Mol Neurodegener
Glavni autori: Wang, Xue, Allen, Mariet, Li, Shaoyu, Quicksall, Zachary S., Patel, Tulsi A., Carnwath, Troy P., Reddy, Joseph S., Carrasquillo, Minerva M., Lincoln, Sarah J., Nguyen, Thuy T., Malphrus, Kimberly G., Dickson, Dennis W., Crook, Julia E., Asmann, Yan W., Ertekin-Taner, Nilüfer
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359236/
https://ncbi.nlm.nih.gov/pubmed/32660529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00392-6
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