Nanotherapy delivery of c-myc inhibitor targets Protumor Macrophages and preserves Antitumor Macrophages in Breast Cancer

Tumor-associated macrophages (TAMs) enhance tumor growth in mice and are correlated with a worse prognosis for breast cancer patients. While early therapies sought to deplete all macrophages, current therapeutics aim to reprogram pro-tumor macrophages (M2) and preserve those necessary for anti-tumor...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Esser, Alison K., Ross, Michael H., Fontana, Francesca, Su, Xinming, Gabay, Ariel, Fox, Gregory C., Xu, Yalin, Xiang, Jingyu, Schmieder, Anne H., Yang, Xiaoxia, Cui, Grace, Scott, Michael, Achilefu, Samuel, Chauhan, Jay, Fletcher, Steven, Lanza, Gregory M., Weilbaecher, Katherine N.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359087/
https://ncbi.nlm.nih.gov/pubmed/32685002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.44523
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