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A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy
AIMS: The activity of the transcription factor c-Myc is dependent upon heterodimerization with Max to control target gene transcription. Small-molecule inhibitors of c-Myc–Max have exhibited low potency and poor water solubility and are therefore unsuitable for in vivo application. We hypothesized t...
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| Publicado no: | Nanomedicine (Lond) |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665613/ https://ncbi.nlm.nih.gov/pubmed/25600969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.14.101 |
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