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cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4

Direct regulation of the pacemaker “funny” current (I(f)) by cyclic AMP (cAMP) underlies heart rate modulation by the autonomic nervous system. At the molecular level, cAMP activates hyperpolarization-activated cyclic nucleotide-gated (HCN) channels that drive I(f) in sinoatrial node (SAN) myocytes....

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Detaylı Bibliyografya
Yayımlandı:Front Physiol
Asıl Yazarlar: Porro, Alessandro, Thiel, Gerhard, Moroni, Anna, Saponaro, Andrea
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358946/
https://ncbi.nlm.nih.gov/pubmed/32733276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00771
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