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Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism

β-Lactam antibiotics are the most widely prescribed antibacterial drugs due to their low toxicity and broad spectrum. Their action is counteracted by different resistance mechanisms developed by bacteria. Among them, the most common strategy is the expression of β-lactamases, enzymes that hydrolyze...

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Detaylı Bibliyografya
Yayımlandı:Biomolecules
Asıl Yazarlar: Palacios, Antonela R., Rossi, María-Agustina, Mahler, Graciela S., Vila, Alejandro J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356002/
https://ncbi.nlm.nih.gov/pubmed/32503337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060854
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