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Role of zinc content on the catalytic efficiency of B1 metallo β-lactamases
Metallo β-lactamases (MβL's) are enzymes naturally evolved by bacterial strains under the evolutionary pressure of β-lactam antibiotic clinical use. They have a broad substrate spectrum and are resistant to all the clinically useful inhibitors, representing a potential risk of infection if mass...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597527/ https://ncbi.nlm.nih.gov/pubmed/17305336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0657556 |
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