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Overcoming differences: the catalytic mechanism of metallo-β-lactamases

Metallo-β-lactamases are the latest resistance mechanism of pathogenic and opportunistic bacteria against carbapenems, considered as last resort drugs. The worldwide spread of genes coding for these enzymes, together with the lack of a clinically useful inhibitor, have raised a sign of alarm. Inhibi...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Meini, María-Rocío, Llarrull, Leticia I., Vila, Alejandro J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640939/
https://ncbi.nlm.nih.gov/pubmed/26297824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.08.015
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