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Overcoming differences: the catalytic mechanism of metallo-β-lactamases

Metallo-β-lactamases are the latest resistance mechanism of pathogenic and opportunistic bacteria against carbapenems, considered as last resort drugs. The worldwide spread of genes coding for these enzymes, together with the lack of a clinically useful inhibitor, have raised a sign of alarm. Inhibi...

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Bibliografiske detaljer
Udgivet i:FEBS Lett
Main Authors: Meini, María-Rocío, Llarrull, Leticia I., Vila, Alejandro J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640939/
https://ncbi.nlm.nih.gov/pubmed/26297824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.08.015
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