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Overcoming differences: the catalytic mechanism of metallo-β-lactamases

Metallo-β-lactamases are the latest resistance mechanism of pathogenic and opportunistic bacteria against carbapenems, considered as last resort drugs. The worldwide spread of genes coding for these enzymes, together with the lack of a clinically useful inhibitor, have raised a sign of alarm. Inhibi...

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Publicat a:FEBS Lett
Autors principals: Meini, María-Rocío, Llarrull, Leticia I., Vila, Alejandro J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640939/
https://ncbi.nlm.nih.gov/pubmed/26297824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.08.015
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