A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A(2) on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A(2)α

Phospholipase A(2)s constitute a wide group of lipid-modifying enzymes which display a variety of functions in innate immune responses. In this work, we utilized mass spectrometry-based lipidomic approaches to investigate the action of Asp-49 Ca(2+)-dependent secreted phospholipase A(2) (sPLA(2)) (M...

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Publicado en:Biomolecules
Main Authors: Rodríguez, Juan P., Leiguez, Elbio, Guijas, Carlos, Lomonte, Bruno, Gutiérrez, José M., Teixeira, Catarina, Balboa, María A., Balsinde, Jesús
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355433/
https://ncbi.nlm.nih.gov/pubmed/32532115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060891
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