A Representative GIIA Phospholipase A(2) Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development

Adipose tissue secretes proinflammatory mediators which promote systemic and adipose tissue inflammation seen in obesity. Group IIA (GIIA)-secreted phospholipase A(2) (sPLA(2)) enzymes are found to be elevated in plasma and adipose tissue from obese patients and are active during inflammation, gener...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Leiguez, Elbio, Motta, Priscila, Maia Marques, Rodrigo, Lomonte, Bruno, Sampaio, Suely Vilela, Teixeira, Catarina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760919/
https://ncbi.nlm.nih.gov/pubmed/33255269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121593
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