A Lys49 Phospholipase A(2), Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region

MT-II, a Lys49PLA(2) homologue devoid of catalytic activity from B. asper venom, stimulates inflammatory events in macrophages. We investigated the ability of MT-II to induce formation of lipid droplets (LDs), key elements of inflammatory responses, in isolated macrophages and participation of prote...

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Autori principali: Cristina Giannotti, Karina, Leiguez, Elbio, Moreira, Vanessa, Nascimento, Neide Galvão, Lomonte, Bruno, Gutiérrez, José Maria, Lopes de Melo, Robson, Teixeira, Catarina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591195/
https://ncbi.nlm.nih.gov/pubmed/23509782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/807982
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