A Snake Venom-Secreted Phospholipase A(2) Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis

MT-III, a snake venom GIIA sPLA(2), which shares structural and functional features with mammalian GIIA sPLA(2)s, activates macrophage defense functions including lipid droplet (LDs) formation, organelle involved in both lipid metabolism and inflammatory processes. Macrophages (MΦs) loaded with LDs,...

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發表在:Mediators Inflamm
Main Authors: Leiguez, Elbio, Giannotti, Karina Cristina, Viana, Mariana do Nascimento, Matsubara, Márcio Hideki, Fernandes, Cristina Maria, Gutiérrez, José Maria, Lomonte, Bruno, Teixeira, Catarina
格式: Artigo
語言:Inglês
出版: Hindawi 2018
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022332/
https://ncbi.nlm.nih.gov/pubmed/30013451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2547918
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