Загрузка...

MAGGIE: leveraging genetic variation to identify DNA sequence motifs mediating transcription factor binding and function

MOTIVATION: Genetic variation in regulatory elements can alter transcription factor (TF) binding by mutating a TF binding motif, which in turn may affect the activity of the regulatory elements. However, it is unclear which motifs are prone to impact transcriptional regulation if mutated. Current mo...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Bioinformatics
Главные авторы: Shen, Zeyang, Hoeksema, Marten A, Ouyang, Zhengyu, Benner, Christopher, Glass, Christopher K
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355228/
https://ncbi.nlm.nih.gov/pubmed/32657363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa476
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!