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MAGGIE: leveraging genetic variation to identify DNA sequence motifs mediating transcription factor binding and function
MOTIVATION: Genetic variation in regulatory elements can alter transcription factor (TF) binding by mutating a TF binding motif, which in turn may affect the activity of the regulatory elements. However, it is unclear which motifs are prone to impact transcriptional regulation if mutated. Current mo...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7355228/ https://ncbi.nlm.nih.gov/pubmed/32657363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa476 |
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