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MAGGIE: leveraging genetic variation to identify DNA sequence motifs mediating transcription factor binding and function
MOTIVATION: Genetic variation in regulatory elements can alter transcription factor (TF) binding by mutating a TF binding motif, which in turn may affect the activity of the regulatory elements. However, it is unclear which motifs are prone to impact transcriptional regulation if mutated. Current mo...
में बचाया:
| में प्रकाशित: | Bioinformatics |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7355228/ https://ncbi.nlm.nih.gov/pubmed/32657363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa476 |
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