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An Update on the Molecular Basis of Phosphoantigen Recognition by Vγ9Vδ2 T Cells
About 1–5% of human blood T cells are Vγ9Vδ2 T cells. Their hallmark is the expression of T cell antigen receptors (TCR) whose γ-chains contain a rearrangement of Vγ9 with JP (TRGV9JP or Vγ2Jγ1.2) and are paired with Vδ2 (TRDV2)-containing δ-chains. These TCRs respond to phosphoantigens (PAg) such a...
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| Pubblicato in: | Cells |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7348870/ https://ncbi.nlm.nih.gov/pubmed/32527033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061433 |
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