The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals

1–5% of human blood T cells are Vγ9Vδ2 T cells whose T cell receptor (TCR) contain a TRGV9/TRGJP rearrangement and a TRDV2 comprising Vδ2-chain. They respond to phosphoantigens (PAgs) like isopentenyl pyrophosphate or (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate (HMBPP) in a butyrophilin 3 (BTN3)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Fichtner, Alina Suzann, Karunakaran, Mohindar Murugesh, Starick, Lisa, Truman, Richard W., Herrmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829056/
https://ncbi.nlm.nih.gov/pubmed/29527206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00265
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