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Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset

Vγ9Vδ2 T cells are a major γδ T cell population in the human blood expressing a characteristic Vγ9JP rearrangement paired with Vδ2. This cell subset is activated in a TCR-dependent and MHC-unrestricted fashion by so-called phosphoantigens (PAgs). PAgs can be microbial [(E)-4-hydroxy-3-methyl-but-2-e...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fichtner, Alina S., Karunakaran, Mohindar M., Gu, Siyi, Boughter, Christopher T., Borowska, Marta T., Starick, Lisa, Nöhren, Anna, Göbel, Thomas W., Adams, Erin J., Herrmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104304/
https://ncbi.nlm.nih.gov/pubmed/32139608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909474117
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