Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes

Downregulation of BST-2/tetherin and CD4 by HIV-1 viral protein U (Vpu) promotes viral egress and allows infected cells to evade host immunity. Little is known however about the natural variability in these Vpu functions among the genetically diverse viral subtypes that contribute to the HIV-1 pande...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Umviligihozo, Gisele, Cobarrubias, Kyle D., Chandrarathna, Sandali, Jin, Steven W., Reddy, Nicole, Byakwaga, Helen, Muzoora, Conrad, Bwana, Mwebesa B., Lee, Guinevere Q., Hunt, Peter W., Martin, Jeff N., Brumme, Chanson J., Bangsberg, David R., Karita, Etienne, Allen, Susan, Hunter, Eric, Ndung’u, Thumbi, Brumme, Zabrina L., Brockman, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343213/
https://ncbi.nlm.nih.gov/pubmed/32376625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00293-20
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados