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Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes
BACKGROUND: The highly genetically diverse HIV-1 group M subtypes may differ in their biological properties. Nef is an important mediator of viral pathogenicity; however, to date, a comprehensive inter-subtype comparison of Nef in vitro function has not been undertaken. Here, we investigate two of N...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849644/ https://ncbi.nlm.nih.gov/pubmed/24041011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-100 |
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