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R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
G-quadruplex (G4) is a noncanonical secondary structure of DNA or RNA which can enhance or repress gene expression, yet the underlying molecular mechanism remains uncertain. Here we show that when positioned downstream of transcription start site, the orientation of potential G4 forming sequence (PQ...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7341879/ https://ncbi.nlm.nih.gov/pubmed/32636376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17176-7 |
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