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R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation

G-quadruplex (G4) is a noncanonical secondary structure of DNA or RNA which can enhance or repress gene expression, yet the underlying molecular mechanism remains uncertain. Here we show that when positioned downstream of transcription start site, the orientation of potential G4 forming sequence (PQ...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Lee, Chun-Ying, McNerney, Christina, Ma, Kevin, Zhao, Walter, Wang, Ashley, Myong, Sua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341879/
https://ncbi.nlm.nih.gov/pubmed/32636376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17176-7
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