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G-quadruplex conformation and dynamics are determined by loop length and sequence
The quadruplex forming G-rich sequences are unevenly distributed throughout the human genome. Their enrichment in oncogenic promoters and telomeres has generated interest in targeting G-quadruplex (GQ) for an anticancer therapy. Here, we present a quantitative analysis on the conformations and dynam...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081081/ https://ncbi.nlm.nih.gov/pubmed/24920827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku464 |
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