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G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders
Genomic DNA and cellular RNAs can form a variety of non-B secondary structures, including G-quadruplex (G4) and R-loops. G4s are constituted by stacked guanine tetrads held together by Hoogsteen hydrogen bonds and can form at key regulatory sites of eukaryote genomes and transcripts, including gene...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7708042/ https://ncbi.nlm.nih.gov/pubmed/33137181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa944 |
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