The aptamer BT200 effectively inhibits von Willebrand factor (VWF) dependent platelet function after stimulated VWF release by desmopressin or endotoxin

Von Willebrand factor (VWF) plays a major role in arterial thrombosis. Antiplatelet drugs induce only a moderate relative risk reduction after atherothrombosis, and their inhibitory effects are compromised under high shear rates when VWF levels are increased. Therefore, we investigated the ex vivo e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Kovacevic, Katarina D., Buchtele, Nina, Schoergenhofer, Christian, Derhaschnig, Ulla, Gelbenegger, Georg, Brostjan, Christine, Zhu, Shuhao, Gilbert, James C., Jilma, Bernd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341806/
https://ncbi.nlm.nih.gov/pubmed/32636459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68125-9
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak