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Inferring Parameters of the Distribution of Fitness Effects of New Mutations When Beneficial Mutations Are Strongly Advantageous and Rare

Characterizing the distribution of fitness effects (DFE) for new mutations is central in evolutionary genetics. Analysis of molecular data under the McDonald-Kreitman test has suggested that adaptive substitutions make a substantial contribution to between-species divergence. Methods have been propo...

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Publicat a:G3 (Bethesda)
Autor principal: Booker, Tom R.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341129/
https://ncbi.nlm.nih.gov/pubmed/32371451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401052
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