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A Method for Inferring the Rate of Occurrence and Fitness Effects of Advantageous Mutations
The distribution of fitness effects (DFE) of new mutations is of fundamental importance in evolutionary genetics. Recently, methods have been developed for inferring the DFE that use information from the allele frequency distributions of putatively neutral and selected nucleotide polymorphic variant...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241409/ https://ncbi.nlm.nih.gov/pubmed/21954160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131730 |
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