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A Method for Inferring the Rate of Occurrence and Fitness Effects of Advantageous Mutations

The distribution of fitness effects (DFE) of new mutations is of fundamental importance in evolutionary genetics. Recently, methods have been developed for inferring the DFE that use information from the allele frequency distributions of putatively neutral and selected nucleotide polymorphic variant...

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Detalhes bibliográficos
Main Authors: Schneider, Adrian, Charlesworth, Brian, Eyre-Walker, Adam, Keightley, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241409/
https://ncbi.nlm.nih.gov/pubmed/21954160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131730
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