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Inferring the distribution of mutational effects on fitness in Drosophila

The properties of the distribution of deleterious mutational effects on fitness (DDME) are of fundamental importance for evolutionary genetics. Since it is extremely difficult to determine the nature of this distribution, several methods using various assumptions about the DDME have been developed,...

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Bibliographic Details
Main Authors: Loewe, Laurence, Charlesworth, Brian
Format: Artigo
Language:Inglês
Published: The Royal Society 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686194/
https://ncbi.nlm.nih.gov/pubmed/17148422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsbl.2006.0481
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