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Inference of genome-wide mutation rates and distributions of mutation effects for fitness traits: a simulation study.

The properties and limitations of maximum likelihood (ML) inference of genome-wide mutation rates (U) and parameters of distributions of mutation effects are investigated. Mutation parameters are estimated from simulated experiments in which mutations randomly accumulate in inbred lines. ML produces...

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Detalhes bibliográficos
Autor principal: Keightley, P D
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460396/
https://ncbi.nlm.nih.gov/pubmed/9799279
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