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A Comparison of Models to Infer the Distribution of Fitness Effects of New Mutations
Knowing the distribution of fitness effects (DFE) of new mutations is important for several topics in evolutionary genetics. Existing computational methods with which to infer the DFE based on DNA polymorphism data have frequently assumed that the DFE can be approximated by a unimodal distribution,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606097/ https://ncbi.nlm.nih.gov/pubmed/23341416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.148023 |
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