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Inferring Parameters of the Distribution of Fitness Effects of New Mutations When Beneficial Mutations Are Strongly Advantageous and Rare

Characterizing the distribution of fitness effects (DFE) for new mutations is central in evolutionary genetics. Analysis of molecular data under the McDonald-Kreitman test has suggested that adaptive substitutions make a substantial contribution to between-species divergence. Methods have been propo...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Autor principal: Booker, Tom R.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341129/
https://ncbi.nlm.nih.gov/pubmed/32371451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401052
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