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The distribution of fitness effects of new beneficial mutations in Pseudomonas fluorescens

Theoretical studies of adaptation emphasize the importance of understanding the distribution of fitness effects (DFE) of new mutations. We report the isolation of 100 adaptive mutants—without the biasing influence of natural selection—from an ancestral genotype whose fitness in the niche occupied by...

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Autors principals: McDonald, Michael J., Cooper, Tim F., Beaumont, Hubertus J. E., Rainey, Paul B.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030884/
https://ncbi.nlm.nih.gov/pubmed/20659918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsbl.2010.0547
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