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The Distribution of Fitness Effects of Beneficial Mutations in Pseudomonas aeruginosa

Understanding how beneficial mutations affect fitness is crucial to our understanding of adaptation by natural selection. Here, using adaptation to the antibiotic rifampicin in the opportunistic pathogen Pseudomonas aeruginosa as a model system, we investigate the underlying distribution of fitness...

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Detalhes bibliográficos
Main Authors: MacLean, R. Craig, Buckling, Angus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646133/
https://ncbi.nlm.nih.gov/pubmed/19266075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000406
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