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Mutational neighbourhood and mutation supply rate constrain adaptation in Pseudomonas aeruginosa

Understanding adaptation by natural selection requires understanding the genetic factors that determine which beneficial mutations are available for selection. Here, using experimental evolution of rifampicin-resistant Pseudomonas aeruginosa, we show that different genotypes vary in their capacity f...

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Detalhes bibliográficos
Main Authors: Hall, Alex R., Griffiths, Victoria F., MacLean, R. Craig, Colegrave, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842691/
https://ncbi.nlm.nih.gov/pubmed/19889704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2009.1630
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