Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction

Baseline lung function, quantified as forced expiratory volume in the first second of exhalation (FEV(1)), is a standard diagnostic criterion used by clinicians to identify and classify lung diseases. Using whole-genome sequencing data from the National Heart, Lung, and Blood Institute Trans-Omics f...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Mak, Angel C. Y., Sajuthi, Satria, Joo, Jaehyun, Xiao, Shujie, Sleiman, Patrick M., White, Marquitta J., Lee, Eunice Y., Saef, Benjamin, Hu, Donglei, Gui, Hongsheng, Keys, Kevin L., Lurmann, Fred, Jain, Deepti, Abecasis, Gonçalo, Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Winterkorn, Lara, Reeves, Catherine, Huntsman, Scott, Eng, Celeste, Salazar, Sandra, Oh, Sam S., Gilliland, Frank D., Chen, Zhanghua, Kumar, Rajesh, Martínez, Fernando D., Wu, Ann Chen, Ziv, Elad, Hakonarson, Hakon, Himes, Blanca E., Williams, L. Keoki, Seibold, Max A., Burchard, Esteban G.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337089/
https://ncbi.nlm.nih.gov/pubmed/32327564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303231
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