Mapping the 17q12–21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans

Rationale: The 17q12–21.1 locus is one of the most highly replicated genetic associations with asthma. Individuals of African descent have lower linkage disequilibrium in this region, which could facilitate identifying causal variants. Objectives: To identify functional variants at 17q12–21.1 associ...

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Publicat a:Am J Respir Crit Care Med
Autors principals: Gui, Hongsheng, Levin, Albert M., Hu, Donglei, Sleiman, Patrick, Xiao, Shujie, Mak, Angel C. Y., Yang, Mao, Barczak, Andrea J., Huntsman, Scott, Eng, Celeste, Hochstadt, Samantha, Zhang, Ellen, Whitehouse, Kyle, Simons, Samantha, Cabral, Whitney, Takriti, Sami, Abecasis, Gonçalo, Blackwell, Thomas W., Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Lanfear, David E., Gilliland, Frank, Gauderman, W. James, Kumar, Rajesh, Erle, David J., Martinez, Fernando D., Hakonarson, Hakon, Burchard, Esteban G., Williams, L. Keoki
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2021
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885840/
https://ncbi.nlm.nih.gov/pubmed/32966749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202006-2623OC
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