Mapping the 17q12–21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans

Rationale: The 17q12–21.1 locus is one of the most highly replicated genetic associations with asthma. Individuals of African descent have lower linkage disequilibrium in this region, which could facilitate identifying causal variants. Objectives: To identify functional variants at 17q12–21.1 associ...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Gui, Hongsheng, Levin, Albert M., Hu, Donglei, Sleiman, Patrick, Xiao, Shujie, Mak, Angel C. Y., Yang, Mao, Barczak, Andrea J., Huntsman, Scott, Eng, Celeste, Hochstadt, Samantha, Zhang, Ellen, Whitehouse, Kyle, Simons, Samantha, Cabral, Whitney, Takriti, Sami, Abecasis, Gonçalo, Blackwell, Thomas W., Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Lanfear, David E., Gilliland, Frank, Gauderman, W. James, Kumar, Rajesh, Erle, David J., Martinez, Fernando D., Hakonarson, Hakon, Burchard, Esteban G., Williams, L. Keoki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2021
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885840/
https://ncbi.nlm.nih.gov/pubmed/32966749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202006-2623OC
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