Mapping the 17q12–21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans

Rationale: The 17q12–21.1 locus is one of the most highly replicated genetic associations with asthma. Individuals of African descent have lower linkage disequilibrium in this region, which could facilitate identifying causal variants. Objectives: To identify functional variants at 17q12–21.1 associ...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Gui, Hongsheng, Levin, Albert M., Hu, Donglei, Sleiman, Patrick, Xiao, Shujie, Mak, Angel C. Y., Yang, Mao, Barczak, Andrea J., Huntsman, Scott, Eng, Celeste, Hochstadt, Samantha, Zhang, Ellen, Whitehouse, Kyle, Simons, Samantha, Cabral, Whitney, Takriti, Sami, Abecasis, Gonçalo, Blackwell, Thomas W., Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Lanfear, David E., Gilliland, Frank, Gauderman, W. James, Kumar, Rajesh, Erle, David J., Martinez, Fernando D., Hakonarson, Hakon, Burchard, Esteban G., Williams, L. Keoki
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885840/
https://ncbi.nlm.nih.gov/pubmed/32966749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202006-2623OC
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