Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program

BACKGROUND: Mitochondria support critical cellular functions, such as energy production through oxidative phosphorylation, regulation of reactive oxygen species, apoptosis, and calcium homeostasis. OBJECTIVE: Given the heightened level of cellular activity in patients with asthma, we sought to deter...

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Publicado no:PLoS One
Main Authors: Cocco, Maxwell P., White, Evan, Xiao, Shujie, Hu, Donglei, Mak, Angel, Sleiman, Patrick, Yang, Mao, Bobbitt, Kevin R., Gui, Hongsheng, Levin, Albert M., Hochstadt, Samantha, Whitehouse, Kyle, Rynkowski, Dean, Barczak, Andrea J., Abecasis, Gonçalo, Blackwell, Thomas W., Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Ding, Jun, Lanfear, David E., Gilliland, Frank, Gauderman, W. James, Kumar, Rajesh, Erle, David J., Martinez, Fernando, Hakonarson, Hakon, Burchard, Esteban G., Williams, L. Keoki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688161/
https://ncbi.nlm.nih.gov/pubmed/33237978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242364
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