Llwytho...
Protein-ligand affinity determinations using covalent labeling-mass spectrometry
Determining binding affinity is an important aspect of charactering protein-ligand complexes. Here, we describe an approach based on covalent labeling (CL)-mass spectrometry (MS) that can accurately provide protein-ligand dissociation constants (K(d) values), using diethylpyrocarbonate (DEPC) as the...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Am Soc Mass Spectrom |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2020
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7332385/ https://ncbi.nlm.nih.gov/pubmed/32501685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00131 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|