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Engineered receptors for human cytomegalovirus that are orthogonal to normal human biology
A trimeric glycoprotein complex on the surface of human cytomegalovirus (HCMV) binds to platelet-derived growth factor (PDGF) receptor α (PDGFRα) to mediate host cell recognition and fusion of the viral and cellular membranes. Soluble PDGFRα potently neutralizes HCMV in tissue culture, and its poten...
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| Vydáno v: | PLoS Pathog |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7329128/ https://ncbi.nlm.nih.gov/pubmed/32559251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008647 |
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