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Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype

Human cytomegalovirus (HCMV) is the prototypical human β-herpes virus. Here we perform a systems analysis of the HCMV host-cell transcriptome, using gene set enrichment analysis (GSEA) as an engine to globally map the host–pathogen interaction across two cell types. Our analysis identified several p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Oberstein, Adam, Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625929/
https://ncbi.nlm.nih.gov/pubmed/28874566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710799114
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