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Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts

Human CMV (HCMV) exhibits a broad cell tropism that depends on two virion glycoprotein complexes: a trimeric complex (gH/gL/gO) that facilitates viral infection primarily in fibroblasts and a pentameric complex (gH/gL/pUL128-pUL130-pUL131A) that mediates infection in epithelial and endothelial cells...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Wu, Kai, Oberstein, Adam, Wang, Wei, Shenk, Thomas
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196492/
https://ncbi.nlm.nih.gov/pubmed/30275317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806305115
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