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Human Cytomegalovirus pUL78 G Protein-Coupled Receptor Homologue Is Required for Timely Cell Entry in Epithelial Cells but Not Fibroblasts

Human cytomegalovirus (HCMV) encodes four putative G protein-coupled receptors, including pUL78, whose rodent orthologues are known to be important for replication and spread in their hosts. To investigate the mechanism by which pUL78 contributes to viral replication and pathogenesis, we generated a...

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Detalhes bibliográficos
Main Authors: O'Connor, Christine M., Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486319/
https://ncbi.nlm.nih.gov/pubmed/22915800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05900-11
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