Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma

Epithelial-mesenchymal transition (EMT) is thought to contribute to metastasis and chemoresistance in patients with hepatocellular carcinoma (HCC), leading to their poor prognosis. The genes driving EMT in HCC are not yet fully understood, however. Here, we show that mobilization of Sleeping Beauty...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kodama, Takahiro, Newberg, Justin Y., Kodama, Michiko, Rangel, Roberto, Yoshihara, Kosuke, Tien, Jean C., Parsons, Pamela H., Wu, Hao, Finegold, Milton J., Copeland, Neal G., Jenkins, Nancy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914200/
https://ncbi.nlm.nih.gov/pubmed/27247392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606876113
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