Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma

Epithelial-mesenchymal transition (EMT) is thought to contribute to metastasis and chemoresistance in patients with hepatocellular carcinoma (HCC), leading to their poor prognosis. The genes driving EMT in HCC are not yet fully understood, however. Here, we show that mobilization of Sleeping Beauty...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kodama, Takahiro, Newberg, Justin Y., Kodama, Michiko, Rangel, Roberto, Yoshihara, Kosuke, Tien, Jean C., Parsons, Pamela H., Wu, Hao, Finegold, Milton J., Copeland, Neal G., Jenkins, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914200/
https://ncbi.nlm.nih.gov/pubmed/27247392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606876113
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