Engineering orthogonal human O-linked glycoprotein biosynthesis in bacteria

A major objective of synthetic glycobiology is to re-engineer existing cellular glycosylation pathways from the top-down or construct non-natural ones from the bottom-up for new and useful purposes. Here, we developed a set of orthogonal pathways for eukaryotic O-linked protein glycosylation in Esch...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Natarajan, Aravind, Jaroentomeechai, Thapakorn, Cabrera-Sánchez, Marielisa, Mohammed, Jody C., Cox, Emily C., Young, Olivia, Shajahan, Asif, Vilkhovoy, Michael, Vadhin, Sandra, Varner, Jeffrey D., Azadi, Parastoo, DeLisa, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857696/
https://ncbi.nlm.nih.gov/pubmed/32719555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0595-9
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